Hieff Trans^®脂质体核酸转染试剂是一种多用途的脂质体转染试剂，适用于DNA、RNA和寡核苷酸的转染，对大多数真核细胞具有很高的转染效率。其独特的配方使其可直接加入培养基中，血清的存在不会影响转染效率，这样可以减少去除血清对细胞的损伤。转染后不需要除去核酸-Hieff Trans^®复合物或更换新鲜培养基，也可在4～6小时后除去。

Hieff Trans^®脂质体核酸转染试剂以无菌的液体形式提供。通常情况下对于 24 孔板转染，每次用1.5 μL左右，则1 mL 约可做660 次转染；对于6孔板，每次用6 μL左右，则1 mL约可做160 次转染。

[1] Liu R, Yang J, Yao J, et al. Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins. Nat Biotechnol. 2022;40(5):779-786. doi:10.1038/s41587-021-01112-1(IF:54.908)
[2] Fan Y, Wang J, Jin W, et al. CircNR3C2 promotes HRD1-mediated tumor-suppressive effect via sponging miR-513a-3p in triple-negative breast cancer. Mol Cancer. 2021;20(1):25. Published 2021 Feb 2. doi:10.1186/s12943-021-01321-x(IF:27.401)
[3] Tao R, Zhao Y, Chu H, et al. Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism. Nat Methods. 2017;14(7):720-728. doi:10.1038/nmeth.4306(IF:25.062)
[4] Zhang Q, He X, Yao S, et al. Ablation of Mto1 in zebrafish exhibited hypertrophic cardiomyopathy manifested by mitochondrion RNA maturation deficiency. Nucleic Acids Res. 2021;49(8):4689-4704. doi:10.1093/nar/gkab228(IF:16.971)
[5] Liang Y, Lu Q, Li W, et al. Reactivation of tumour suppressor in breast cancer by enhancer switching through NamiRNA network. Nucleic Acids Res. 2021;49(15):8556-8572. doi:10.1093/nar/gkab626(IF:16.971)
[6] Wu S, Cao R, Tao B, et al. Pyruvate Facilitates FACT-Mediated γH2AX Loading to Chromatin and Promotes the Radiation Resistance of Glioblastoma. Adv Sci (Weinh). 2022;9(8):e2104055. doi:10.1002/advs.202104055(IF:16.806)
[7] Luo Q, Wu X, Zhao P, et al. OTUD1 Activates Caspase-Independent and Caspase-Dependent Apoptosis by Promoting AIF Nuclear Translocation and MCL1 Degradation. Adv Sci (Weinh). 2021;8(8):2002874. Published 2021 Feb 8. doi:10.1002/advs.202002874(IF:16.806)
[8] Chen S, Cao X, Zhang J, Wu W, Zhang B, Zhao F. circVAMP3 Drives CAPRIN1 Phase Separation and Inhibits Hepatocellular Carcinoma by Suppressing c-Myc Translation. Adv Sci (Weinh). 2022;9(8):e2103817. doi:10.1002/advs.202103817(IF:16.806)
[9] Yan JM, Zhang WK, Yan LN, Jiao YJ, Zhou CM, Yu XJ. Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress. Autophagy. 2022;18(7):1599-1612. doi:10.1080/15548627.2021.1994296(IF:16.016)
[10] Xu X, Zhang J, Tian Y, et al. CircRNA inhibits DNA damage repair by interacting with host gene. Mol Cancer. 2020;19(1):128. Published 2020 Aug 24. doi:10.1186/s12943-020-01246-x(IF:15.302)
[11] Huang K, Chen X, Li C, et al. Structure-based investigation of fluorogenic Pepper aptamer. Nat Chem Biol. 2021;17(12):1289-1295. doi:10.1038/s41589-021-00884-6(IF:15.040)
[12] Li T, Chen X, Qian Y, et al. A synthetic BRET-based optogenetic device for pulsatile transgene expression enabling glucose homeostasis in mice. Nat Commun. 2021;12(1):615. Published 2021 Jan 27. doi:10.1038/s41467-021-20913-1(IF:14.919)
[13] Liu Z, Chen S, Lai L, Li Z. Inhibition of base editors with anti-deaminases derived from viruses. Nat Commun. 2022;13(1):597. Published 2022 Feb 1. doi:10.1038/s41467-022-28300-0(IF:14.919)
[14] Wu C, Wang C, Zheng J, et al. Vacuolization in Cytoplasm and Cell Membrane Permeability Enhancement Triggered by Micrometer-Sized Graphene Oxide. ACS Nano. 2015;9(8):7913-7924. doi:10.1021/acsnano.5b01685(IF:12.881)
[15] Zou Y, Wang A, Shi M, et al. Analysis of redox landscapes and dynamics in living cells and in vivo using genetically encoded fluorescent sensors. Nat Protoc. 2018;13(10):2362-2386. doi:10.1038/s41596-018-0042-5(IF:12.423)
[16] Sun X, Peng X, Cao Y, Zhou Y, Sun Y. ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling. Nat Commun. 2020;11(1):2984. Published 2020 Jun 12. doi:10.1038/s41467-020-16799-0(IF:12.121)
[17] Song L, Liu Z, Hu HH, et al. Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy. Nat Commun. 2020;11(1):5842. Published 2020 Nov 17. doi:10.1038/s41467-020-19694-w(IF:12.121)
[18] Shui S, Zhao Z, Wang H, Conrad M, Liu G. Non-enzymatic lipid peroxidation initiated by photodynamic therapy drives a distinct ferroptosis-like cell death pathway. Redox Biol. 2021;45:102056. doi:10.1016/j.redox.2021.102056(IF:11.799)
[19] Du L, Xie Y, Zheng K, et al. Oxidative stress transforms 3CLpro into an insoluble and more active form to promote SARS-CoV-2 replication [published online ahead of print, 2021 Nov 26]. Redox Biol. 2021;48:102199. doi:10.1016/j.redox.2021.102199(IF:11.799)
[20] Cen M, Ouyang W, Zhang W, et al. MitoQ protects against hyperpermeability of endothelium barrier in acute lung injury via a Nrf2-dependent mechanism. Redox Biol. 2021;41:101936. doi:10.1016/j.redox.2021.101936(IF:11.799)
[21] Sun X, Peng X, Cao Y, Zhou Y, Sun Y. ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling. Nat Commun. 2020;11(1):2984. Published 2020 Jun 12. doi:10.1038/s41467-020-16799-0(IF:11.614)
[22] Liu W, Zhan Z, Zhang M, et al. KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1. Theranostics. 2021;11(13):6278-6292. Published 2021 Apr 15. doi:10.7150/thno.57455(IF:11.556)
[23] Hao Q, Li J, Zhang Q, et al. Single-cell transcriptomes reveal heterogeneity of high-grade serous ovarian carcinoma. Clin Transl Med. 2021;11(8):e500. doi:10.1002/ctm2.500(IF:11.492)
[24] Zhang Y, Yu X, Sun R, et al. Splicing factor arginine/serine-rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome-based cellular communication. Clin Transl Med. 2022;12(2):e684. doi:10.1002/ctm2.684(IF:11.492)
[25] Liu Z, Chen S, Xie W, et al. Versatile and efficient in vivo genome editing with compact Streptococcus pasteurianus Cas9. Mol Ther. 2022;30(1):256-267. doi:10.1016/j.ymthe.2021.06.013(IF:11.454)
[26] Tang X, Deng Z, Ding P, et al. A novel protein encoded by circHNRNPU promotes multiple myeloma progression by regulating the bone marrow microenvironment and alternative splicing. J Exp Clin Cancer Res. 2022;41(1):85. Published 2022 Mar 8. doi:10.1186/s13046-022-02276-7(IF:11.161)
[27] Gu C, Wang Y, Zhang L, et al. AHSA1 is a promising therapeutic target for cellular proliferation and proteasome inhibitor resistance in multiple myeloma. J Exp Clin Cancer Res. 2022;41(1):11. Published 2022 Jan 6. doi:10.1186/s13046-021-02220-1(IF:11.161)
[28] Chen P, Zhou J, Wan Y, et al. A Cas12a ortholog with stringent PAM recognition followed by low off-target editing rates for genome editing. Genome Biol. 2020;21(1):78. Published 2020 Mar 25. doi:10.1186/s13059-020-01989-2(IF:10.806)
[29] Wu Y, Zhao Y, Huan L, et al. An LTR Retrotransposon-Derived Long Noncoding RNA lncMER52A Promotes Hepatocellular Carcinoma Progression by Binding p120-Catenin. Cancer Res. 2020;80(5):976-987. doi:10.1158/0008-5472.CAN-19-2115(IF:9.727)
[30] Wang X, Chen M, Fang L. hsa_circ_0068631 promotes breast cancer progression through c-Myc by binding to EIF4A3. Mol Ther Nucleic Acids. 2021;26:122-134. Published 2021 Jul 16. doi:10.1016/j.omtn.2021.07.003(IF:8.886)
[31] Zhao D, Qian Y, Li J, Li Z, Lai L. Highly efficient A-to-G base editing by ABE8.17 in rabbits. Mol Ther Nucleic Acids. 2022;27:1156-1163. Published 2022 Jan 28. doi:10.1016/j.omtn.2022.01.019(IF:8.886)
[32] Jia J, Kang Q, Liu S, et al. Artemether and aspterric acid induce pancreatic alpha cells to transdifferentiate into beta cells in zebrafish. Br J Pharmacol. 2022;179(9):1962-1977. doi:10.1111/bph.15769(IF:8.740)
[33] Qiao S, Lv C, Tao Y, et al. Arctigenin disrupts NLRP3 inflammasome assembly in colonic macrophages via downregulating fatty acid oxidation to prevent colitis-associated cancer. Cancer Lett. 2020;491:162-179. doi:10.1016/j.canlet.2020.08.033(IF:8.679)
[34] Jin R, Zhao A, Han S, et al. The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis. Cell Death Dis. 2021;12(10):942. Published 2021 Oct 13. doi:10.1038/s41419-021-04249-8(IF:8.469)
[35] Hao Q, Chen J, Liao J, et al. p53 induces ARTS to promote mitochondrial apoptosis. Cell Death Dis. 2021;12(2):204. Published 2021 Feb 24. doi:10.1038/s41419-021-03463-8(IF:8.469)
[36] Zhu C, Zhang L, Zhao S, et al. UPF1 promotes chemoresistance to oxaliplatin through regulation of TOP2A activity and maintenance of stemness in colorectal cancer. Cell Death Dis. 2021;12(6):519. Published 2021 May 21. doi:10.1038/s41419-021-03798-2(IF:8.469)
[37] Liu J, Zang Y, Ma C, et al. Pseudophosphatase STYX is induced by Helicobacter pylori and promotes gastric cancer progression by inhibiting FBXO31 function. Cell Death Dis. 2022;13(3):268. Published 2022 Mar 25. doi:10.1038/s41419-022-04696-x(IF:8.469)
[38] Liu H, Xing R, Ou Z, et al. G-protein-coupled receptor GPR17 inhibits glioma development by increasing polycomb repressive complex 1-mediated ROS production. Cell Death Dis. 2021;12(6):610. Published 2021 Jun 12. doi:10.1038/s41419-021-03897-0(IF:8.469)
[39] Li W, Yang S, Xu P, et al. SARS-CoV-2 RNA elements share human sequence identity and upregulate hyaluronan via NamiRNA-enhancer network. EBioMedicine. 2022;76:103861. doi:10.1016/j.ebiom.2022.103861(IF:8.143)
[40] Luo Q, Wu X, Nan Y, et al. TRIM32/USP11 Balances ARID1A Stability and the Oncogenic/Tumor-Suppressive Status of Squamous Cell Carcinoma. Cell Rep. 2020;30(1):98-111.e5. doi:10.1016/j.celrep.2019.12.017(IF:8.109)
[41] Zhang K, Zhao X, Chen X, et al. Enhanced Therapeutic Effects of Mesenchymal Stem Cell-Derived Exosomes with an Injectable Hydrogel for Hindlimb Ischemia Treatment. ACS Appl Mater Interfaces. 2018;10(36):30081-30091. doi:10.1021/acsami.8b08449(IF:8.097)
[42] Luo Q, Wu X, Chang W, et al. ARID1A prevents squamous cell carcinoma initiation and chemoresistance by antagonizing pRb/E2F1/c-Myc-mediated cancer stemness. Cell Death Differ. 2020;27(6):1981-1997. doi:10.1038/s41418-019-0475-6(IF:8.086)
[43] Zhang X, Qi Z, Yin H, Yang G. Interaction between p53 and Ras signaling controls cisplatin resistance via HDAC4- and HIF-1α-mediated regulation of apoptosis and autophagy. Theranostics. 2019;9(4):1096-1114. Published 2019 Jan 30. doi:10.7150/thno.29673(IF:8.063)
[44] Ji P, Wu W, Chen S, et al. Expanded Expression Landscape and Prioritization of Circular RNAs in Mammals. Cell Rep. 2019;26(12):3444-3460.e5. doi:10.1016/j.celrep.2019.02.078(IF:7.815)
[45] Guo X, Xu X, Li T, et al. NLRP3 Inflammasome Activation of Mast Cells by Estrogen via the Nuclear-Initiated Signaling Pathway Contributes to the Development of Endometriosis. Front Immunol. 2021;12:749979. Published 2021 Sep 22. doi:10.3389/fimmu.2021.749979(IF:7.561)
[46] Yang X, Wang Y, Lu P, et al. PEBP1 suppresses HIV transcription and induces latency by inactivating MAPK/NF-κB signaling. EMBO Rep. 2020;21(11):e49305. doi:10.15252/embr.201949305(IF:7.497)
[47] Feng C, Chen T, Mao D, Zhang F, Tian B, Zhu X. Construction of a Ternary Complex Based DNA Logic Nanomachine for a Highly Accurate Imaging Analysis of Cancer Cells. ACS Sens. 2020;5(10):3116-3123. doi:10.1021/acssensors.0c01166(IF:7.333)
[48] Jiang Y, Tong K, Yao R, et al. Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV-2 replication. Cell Biosci. 2021;11(1):140. Published 2021 Jul 22. doi:10.1186/s13578-021-00644-y(IF:7.133)
[49] He T, Shen H, Wang S, et al. MicroRNA-3613-5p Promotes Lung Adenocarcinoma Cell Proliferation through a RELA and AKT/MAPK Positive Feedback Loop. Mol Ther Nucleic Acids. 2020;22:572-583. Published 2020 Sep 26. doi:10.1016/j.omtn.2020.09.024(IF:7.032)
[50] Liu J, Xu W, Wang K, et al. Congenital cataract-causing mutation βB1-L116P is prone to amyloid fibrils aggregation and protease degradation with low structural stability. Int J Biol Macromol. 2022;195:475-482. doi:10.1016/j.ijbiomac.2021.12.044(IF:6.953)
[51] Xu J, Wang H, Wu C, et al. Pathogenic mechanism of congenital cataract caused by the CRYBA1/A3-G91del variant and related intervention strategies. Int J Biol Macromol. 2021;189:44-52. doi:10.1016/j.ijbiomac.2021.08.111(IF:6.953)
[52] Duan Y, Jiang N, Chen J, Chen J. Expression, localization and metabolic function of "resurrected" human urate oxidase in human hepatocytes. Int J Biol Macromol. 2021;175:30-39. doi:10.1016/j.ijbiomac.2021.01.163(IF:6.953)
[53] Wang C, Zhang H, Fu J, et al. Bartonella type IV secretion effector BepC induces stress fiber formation through activation of GEF-H1. PLoS Pathog. 2021;17(1):e1009065. Published 2021 Jan 28. doi:10.1371/journal.ppat.1009065(IF:6.823)
[54] Li Y, Zhang J, Li S, et al. Heterogeneous Nuclear Ribonucleoprotein A1 Loads Batched Tumor-Promoting MicroRNAs Into Small Extracellular Vesicles With the Assist of Caveolin-1 in A549 Cells. Front Cell Dev Biol. 2021;9:687912. Published 2021 Jun 17. doi:10.3389/fcell.2021.687912(IF:6.684)
[55] Huang Y, Xie B, Cao M, et al. LncRNA RNA Component of Mitochondrial RNA-Processing Endoribonuclease Promotes AKT-Dependent Breast Cancer Growth and Migration by Trapping MicroRNA-206. Front Cell Dev Biol. 2021;9:730538. Published 2021 Sep 21. doi:10.3389/fcell.2021.730538(IF:6.684)
[56] Liu WL, Guan Q, Wen D, et al. PRDM16 Inhibits Cell Proliferation and Migration via Epithelial-to-Mesenchymal Transition by Directly Targeting Pyruvate Carboxylase in Papillary Thyroid Cancer. Front Cell Dev Biol. 2021;9:723777. Published 2021 Nov 2. doi:10.3389/fcell.2021.723777(IF:6.684)
[57] Li F, Zhao H, Su M, et al. HnRNP-F regulates EMT in bladder cancer by mediating the stabilization of Snail1 mRNA by binding to its 3' UTR. EBioMedicine. 2019;45:208-219. doi:10.1016/j.ebiom.2019.06.017(IF:6.680)
[58] Li L, Zhang C, Wang P, et al. Imaging the Redox States of Live Cells with the Time-Resolved Fluorescence of Genetically Encoded Biosensors. Anal Chem. 2019;91(6):3869-3876. doi:10.1021/acs.analchem.8b04292(IF:6.350)
[59] Meng J, Liu K, Shao Y, et al. ID1 confers cancer cell chemoresistance through STAT3/ATF6-mediated induction of autophagy. Cell Death Dis. 2020;11(2):137. Published 2020 Feb 20. doi:10.1038/s41419-020-2327-1(IF:6.304)
[60] Hao Q, Wang J, Chen Y, et al. Dual regulation of p53 by the ribosome maturation factor SBDS. Cell Death Dis. 2020;11(3):197. Published 2020 Mar 20. doi:10.1038/s41419-020-2393-4(IF:6.304)
[61] Han T, Tong J, Wang M, et al. Olaparib Induces RPL5/RPL11-Dependent p53 Activation via Nucleolar Stress. Front Oncol. 2022;12:821366. Published 2022 Jun 3. doi:10.3389/fonc.2022.821366(IF:6.244)
[62] Cao G, Li P, He X, et al. FHL3 Contributes to EMT and Chemotherapy Resistance Through Up-Regulation of Slug and Activation of TGFβ/Smad-Independent Pathways in Gastric Cancer. Front Oncol. 2021;11:649029. Published 2021 Jun 4. doi:10.3389/fonc.2021.649029(IF:6.244)
[63] Tang C, Wang X, Ji C, et al. The Role of miR-640: A Potential Suppressor in Breast Cancer via Wnt7b/β-catenin Signaling Pathway. Front Oncol. 2021;11:645682. Published 2021 Apr 12. doi:10.3389/fonc.2021.645682(IF:6.244)
[64] Huang C, Hao Q, Shi G, Zhou X, Zhang Y. BCL7C suppresses ovarian cancer growth by inactivating mutant p53. J Mol Cell Biol. 2021;13(2):141-150. doi:10.1093/jmcb/mjaa065(IF:6.216)
[65] Xu C, Zhang M, Bian L, Li Y, Yao Y, Li D. N-glycosylated SGK196 suppresses the metastasis of basal-like breast cancer cells. Oncogenesis. 2020;9(1):4. Published 2020 Jan 8. doi:10.1038/s41389-019-0188-1(IF:6.119)
[66] Li J, Zhu D, Hu S, Nie Y. CRISPR-CasRx knock-in mice for RNA degradation [published online ahead of print, 2022 Apr 7]. Sci China Life Sci. 2022;10.1007/s11427-021-2059-5. doi:10.1007/s11427-021-2059-5(IF:6.038)
[67] Liu Z, Chen S, Jia Y, et al. Efficient and high-fidelity base editor with expanded PAM compatibility for cytidine dinucleotide. Sci China Life Sci. 2021;64(8):1355-1367. doi:10.1007/s11427-020-1775-2(IF:6.038)
[68] Tao R, Shi M, Zou Y, et al. Multicoloured fluorescent indicators for live-cell and in vivo imaging of inorganic mercury dynamics. Free Radic Biol Med. 2018;121:26-37. doi:10.1016/j.freeradbiomed.2018.04.562(IF:6.020)
[69] Chen Y, Hao Q, Wang J, et al. Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53. Cell Death Dis. 2019;10(10):737. Published 2019 Sep 30. doi:10.1038/s41419-019-1977-3(IF:5.959)
[70] Lu W, Wang Q, Xu C, et al. SUMOylation is essential for Sirt2 tumor-suppressor function in neuroblastoma. Neoplasia. 2021;23(1):129-139. doi:10.1016/j.neo.2020.11.013(IF:5.696)
[71] Zhou X, Jian W, Luo Q, et al. Circular RNA_0006014 promotes breast cancer progression through sponging miR-885-3p to regulate NTRK2 and PIK3/AKT pathway. Aging (Albany NY). 2022;14(7):3105-3128. doi:10.18632/aging.203996(IF:5.682)
[72] Ji C, Hu J, Wang X, et al. Hsa_circ_0053063 inhibits breast cancer cell proliferation via hsa_circ_0053063/hsa-miR-330-3p/PDCD4 axis. Aging (Albany NY). 2021;13(7):9627-9645. doi:10.18632/aging.202707(IF:5.682)
[73] Li PP, Li RG, Huang YQ, Lu JP, Zhang WJ, Wang ZY. LncRNA OTUD6B-AS1 promotes paclitaxel resistance in triple negative breast cancer by regulation of miR-26a-5p/MTDH pathway-mediated autophagy and genomic instability. Aging (Albany NY). 2021;13(21):24171-24191. doi:10.18632/aging.203672(IF:5.682)
[74] Jin R, Gao Q, Yin C, et al. The CD146-HIF-1α axis regulates epithelial cell migration and alveolar maturation in a mouse model of bronchopulmonary dysplasia. Lab Invest. 2022;102(8):794-804. doi:10.1038/s41374-022-00773-z(IF:5.662)
[75] Wang X, Lu X, Wang P, et al. SRSF9 promotes colorectal cancer progression via stabilizing DSN1 mRNA in an m6A-related manner. J Transl Med. 2022;20(1):198. Published 2022 May 4. doi:10.1186/s12967-022-03399-3(IF:5.531)
[76] Zhang L, Li YM, Zeng XX, et al. Galectin-3- Mediated Transdifferentiation of Pulmonary Artery Endothelial Cells Contributes to Hypoxic Pulmonary Vascular Remodeling. Cell Physiol Biochem. 2018;51(2):763-777. doi:10.1159/000495331(IF:5.500)
[77] Li J, Yang YL, Li LZ, et al. Succinate accumulation impairs cardiac pyruvate dehydrogenase activity through GRP91-dependent and independent signaling pathways: Therapeutic effects of ginsenoside Rb1. Biochim Biophys Acta Mol Basis Dis. 2017;1863(11):2835-2847. doi:10.1016/j.bbadis.2017.07.017(IF:5.476)
[78] Luo Z, Hu H, Liu S, Zhang Z, Li Y, Zhou L. Comprehensive analysis of the translatome reveals the relationship between the translational and transcriptional control in high fat diet-induced liver steatosis. RNA Biol. 2021;18(6):863-874. doi:10.1080/15476286.2020.1827193(IF:5.350)
[79] Cheng Y, Wang Q, Zhang Z, et al. Saucerneol attenuates nasopharyngeal carcinoma cells proliferation and metastasis through selectively targeting Grp94. Phytomedicine. 2022;101:154133. doi:10.1016/j.phymed.2022.154133(IF:5.340)
[80] Jiang H, Song S, Li J, Yin Q, Hu S, Nie Y. Establishment and characterization of an immortalized epicardial cell line [published online ahead of print, 2021 Apr 6]. J Cell Mol Med. 2021;25(13):6070-6081. doi:10.1111/jcmm.16496(IF:5.310)
[81] Xu P, Tang J, He ZG. Induction of Endoplasmic Reticulum Stress by CdhM Mediates Apoptosis of Macrophage During Mycobacterium tuberculosis Infection. Front Cell Infect Microbiol. 2022;12:877265. Published 2022 Apr 4. doi:10.3389/fcimb.2022.877265(IF:5.293)
[82] Xu Y, Chen X, Zhao C, et al. MiR-99b-5p Attenuates Adipogenesis by Targeting SCD1 and Lpin1 in 3T3-L1 Cells. J Agric Food Chem. 2021;69(8):2564-2575. doi:10.1021/acs.jafc.0c07451(IF:5.279)
[83] Cai S, Weng Y, Miao F. MicroRNA-194 inhibits PRC1 activation of the Wnt/β-catenin signaling pathway to prevent tumorigenesis by elevating self-renewal of non-side population cells and side population cells in esophageal cancer stem cells. Cell Tissue Res. 2021;384(2):353-366. doi:10.1007/s00441-021-03412-z(IF:5.249)
[84] Song L, Zhang L, Zhou Y, et al. ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma. Cell Death Discov. 2022;8(1):219. Published 2022 Apr 21. doi:10.1038/s41420-022-01023-3(IF:5.241)
[85] Zhang X, Li Y, Ji J, et al. Gadd45g initiates embryonic stem cell differentiation and inhibits breast cell carcinogenesis. Cell Death Discov. 2021;7(1):271. Published 2021 Oct 2. doi:10.1038/s41420-021-00667-x(IF:5.241)
[86] Wang X, Song H, Fang L, Wu T. EIF4A3-mediated circPRKCI expression promotes triple-negative breast cancer progression by regulating WBP2 and PI3K/AKT signaling pathway. Cell Death Discov. 2022;8(1):92. Published 2022 Mar 2. doi:10.1038/s41420-022-00892-y(IF:5.241)
[87] Sun H, Xu X, Luo J, et al. Mechanisms of PiT2-loop7 Missense Mutations Induced Pi Dyshomeostasis [published online ahead of print, 2022 Jun 17]. Neurosci Bull. 2022;10.1007/s12264-022-00893-y. doi:10.1007/s12264-022-00893-y(IF:5.203)
[88] Wu Q, Huang Y, Gu L, Chang Z, Li GM. OTUB1 stabilizes mismatch repair protein MSH2 by blocking ubiquitination. J Biol Chem. 2021;296:100466. doi:10.1016/j.jbc.2021.100466(IF:5.157)
[89] Ge H, Zhang D, Shi M, Lian X, Zhang Z. Antiproliferative Activity and Potential Mechanism of Marine-Sourced Streptoglutarimide H against Lung Cancer Cells. Mar Drugs. 2021;19(2):79. Published 2021 Jan 31. doi:10.3390/md19020079(IF:5.118)
[90] Zhang Y, Wang Q, Wang Z, et al. Comprehensive Analysis of REST/NRSF Gene in Glioma and Its ceRNA Network Identification. Front Med (Lausanne). 2021;8:739624. Published 2021 Nov 11. doi:10.3389/fmed.2021.739624(IF:5.093)
[91] Li Y, Feng R, Yu X, et al. SLC35E2 promoter mutation as a prognostic marker of esophageal squamous cell carcinoma [published correction appears in Life Sci. 2022 Jun 1;298:120493]. Life Sci. 2022;296:120447. doi:10.1016/j.lfs.2022.120447(IF:5.037)
[92] Chen L, Cheng X, Tu W, et al. Apatinib inhibits glycolysis by suppressing the VEGFR2/AKT1/SOX5/GLUT4 signaling pathway in ovarian cancer cells. Cell Oncol (Dordr). 2019;42(5):679-690. doi:10.1007/s13402-019-00455-x(IF:5.020)
[93] Wang X, Yao Z, Fang L. miR-22-3p/PGC1β Suppresses Breast Cancer Cell Tumorigenesis via PPARγ. PPAR Res. 2021;2021:6661828. Published 2021 Mar 12. doi:10.1155/2021/6661828(IF:4.964)
[94] Li X, Yu H, Liang L, et al. Myricetin ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β signaling via targeting HSP90β. Biochem Pharmacol. 2020;178:114097. doi:10.1016/j.bcp.2020.114097(IF:4.960)
[95] Li B, Xian X, Lin X, et al. Hypoxia Alters the Proteome Profile and Enhances the Angiogenic Potential of Dental Pulp Stem Cell-Derived Exosomes. Biomolecules. 2022;12(4):575. Published 2022 Apr 14. doi:10.3390/biom12040575(IF:4.879)
[96] Bian L, Meng Y, Zhang M, et al. ATM Expression Is Elevated in Established Radiation-Resistant Breast Cancer Cells and Improves DNA Repair Efficiency. Int J Biol Sci. 2020;16(7):1096-1106. Published 2020 Feb 4. doi:10.7150/ijbs.41246(IF:4.858)
[97] Wang Y, Zhao L, Han X, et al. Saikosaponin A Inhibits Triple-Negative Breast Cancer Growth and Metastasis Through Downregulation of CXCR4. Front Oncol. 2020;9:1487. Published 2020 Jan 28. doi:10.3389/fonc.2019.01487(IF:4.848)
[98] Wang X, Lu B, Dai C, et al. Caveolin-1 Promotes Chemoresistance of Gastric Cancer Cells to Cisplatin by Activating WNT/β-Catenin Pathway. Front Oncol. 2020;10:46. Published 2020 Feb 3. doi:10.3389/fonc.2020.00046(IF:4.848)
[99] Li P, Cao G, Zhang Y, et al. FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors. Aging (Albany NY). 2020;12(1):53-69. doi:10.18632/aging.102564(IF:4.831)
[100] Wang S, Hao Q, Li J, et al. Ubiquitin ligase DTX3 empowers mutant p53 to promote ovarian cancer development. Genes Dis. 2020;9(3):705-716. Published 2020 Nov 21. doi:10.1016/j.gendis.2020.11.007(IF:4.803)
[101] Xiong Y, Yi Y, Wang Y, Yang N, Rudd CE, Liu H. Ubc9 Interacts with and SUMOylates the TCR Adaptor SLP-76 for NFAT Transcription in T Cells. J Immunol. 2019;203(11):3023-3036. doi:10.4049/jimmunol.1900556(IF:4.718)
[102] Zhang D, Liu R, Bao C, et al. Development of Acrylamide-Based Rapid and Multicolor Fluorogenic Probes for High Signal-to-Noise Live Cell Imaging. Bioconjug Chem. 2019;30(1):184-191. doi:10.1021/acs.bioconjchem.8b00827(IF:4.485)
[103] Zhou Y, Zhang S, Min Z, Yu Z, Zhang H, Jiao J. Knockdown of circ_0011946 targets miR-216a-5p/BCL2L2 axis to regulate proliferation, migration, invasion and apoptosis of oral squamous cell carcinoma cells. BMC Cancer. 2021;21(1):1085. Published 2021 Oct 7. doi:10.1186/s12885-021-08779-4(IF:4.430)
[104] Wang C, Fu J, Wang M, et al. Bartonella quintana type IV secretion effector BepE-induced selective autophagy by conjugation with K63 polyubiquitin chain. Cell Microbiol. 2019;21(4):e12984. doi:10.1111/cmi.12984(IF:4.410)
[105] Liu J, Chen X, Liu Y, et al. Characterization of SARS-CoV-2 worldwide transmission based on evolutionary dynamics and specific viral mutations in the spike protein. Infect Dis Poverty. 2021;10(1):112. Published 2021 Aug 21. doi:10.1186/s40249-021-00895-4(IF:4.388)
[106] Papadaki S, Wang X, Wang Y, et al. Dual-expression system for blue fluorescent protein optimization. Sci Rep. 2022;12(1):10190. Published 2022 Jun 17. doi:10.1038/s41598-022-13214-0(IF:4.380)
[107] Cai J, Huang H, Hu X, et al. Homoharringtonine Synergized with Gilteritinib Results in the Downregulation of Myeloid Cell Leukemia-1 by Upregulating UBE2L6 in FLT3-ITD-Mutant Acute Myeloid (Leukemia) Cell Lines. J Oncol. 2021;2021:3766428. Published 2021 Sep 21. doi:10.1155/2021/3766428(IF:4.375)
[108] Li M, Liu J, Zhou J, Liu A, Chen E, Yang Q. DNA adduct formation and reduced EIF4A3expression contributes to benzo[a]pyrene-induced DNA damage in human bronchial epithelial BEAS-2B cells. Toxicol Lett. 2021;351:53-64. doi:10.1016/j.toxlet.2021.08.010(IF:4.374)
[109] Jin YY, Lin H, Cao L, et al. A Convenient and Biosafe Replicon with Accessory Genes of SARS-CoV-2 and Its Potential Application in Antiviral Drug Discovery. Virol Sin. 2021;36(5):913-923. doi:10.1007/s12250-021-00385-9(IF:4.327)
[110] Han XR, Wen X, Wang YJ, et al. MicroRNA-140-5p elevates cerebral protection of dexmedetomidine against hypoxic-ischaemic brain damage via the Wnt/β-catenin signalling pathway. J Cell Mol Med. 2018;22(6):3167-3182. doi:10.1111/jcmm.13597(IF:4.302)
[111] Chen S, Liu Z, Yu H, Lai L, Li Z. Efficient multinucleotide deletions using deaminase-Cas9 fusions in human cells [published online ahead of print, 2022 Apr 11]. J Genet Genomics. 2022;S1673-8527(22)00088-1. doi:10.1016/j.jgg.2022.03.007(IF:4.275)
[112] Huang Y, Wang J, Cao F, et al. SHP2 associates with nuclear localization of STAT3: significance in progression and prognosis of colorectal cancer. Sci Rep. 2017;7(1):17597. Published 2017 Dec 14. doi:10.1038/s41598-017-17604-7(IF:4.259)
[113] Wang XY, Zhu BR, Jia Q, Li YM, Wang T, Wang HY. Cinnamtannin D1 Protects Pancreatic β-Cells from Glucolipotoxicity-Induced Apoptosis by Enhancement of Autophagy In Vitro and In Vivo. J Agric Food Chem. 2020;68(45):12617-12630. doi:10.1021/acs.jafc.0c04898(IF:4.192)
[114] Liang K, Mei S, Gao X, Peng S, Zhan J. Dynamics of Endocytosis and Degradation of Antibody-Drug Conjugate T-DM1 in HER2 Positive Cancer Cells. Drug Des Devel Ther. 2021;15:5135-5150. Published 2021 Dec 24. doi:10.2147/DDDT.S344052(IF:4.162)
[115] Liu J, Zhou J, Zhou J, et al. Fine particulate matter exposure induces DNA damage by downregulating Rad51 expression in human bronchial epithelial Beas-2B cells in vitro. Toxicology. 2020;444:152581. doi:10.1016/j.tox.2020.152581(IF:4.099)
[116] Wang J, Zhao Y, Tang Y, Li F, Chen X. The role of lncRNA-MEG/miR-21-5p/PDCD4 axis in spinal cord injury. Am J Transl Res. 2021;13(2):646-658. Published 2021 Feb 15. (IF:4.060)
[117] Wang Q, Zhang Q, Luan S, et al. Adapalene inhibits ovarian cancer ES-2 cells growth by targeting glutamic-oxaloacetic transaminase 1. Bioorg Chem. 2019;93:103315. doi:10.1016/j.bioorg.2019.103315(IF:3.926)
[118] Yang KY, Wu CR, Zheng MZ, et al. Physapubescin I from husk tomato suppresses SW1990 cancer cell growth by targeting kidney-type glutaminase. Bioorg Chem. 2019;92:103186. doi:10.1016/j.bioorg.2019.103186(IF:3.926)
[119] Yu D, Zhao X, Cheng JZ, Wang D, Zhang HH, Han GH. Downregulated microRNA-488 enhances odontoblast differentiation of human dental pulp stem cells via activation of the p38 MAPK signaling pathway [retracted in:  J Cell Physiol. 2022 Apr;237(4):2296]. J Cell Physiol. 2019;234(2):1442-1451. doi:10.1002/jcp.26950(IF:3.923)
[120] Wang BL, Wang Z, Nan X, Zhang QC, Liu W. Downregulation of microRNA-143-5p is required for the promotion of odontoblasts differentiation of human dental pulp stem cells through the activation of the mitogen-activated protein kinases 14-dependent p38 mitogen-activated protein kinases signaling pathway. J Cell Physiol. 2019;234(4):4840-4850. doi:10.1002/jcp.27282(IF:3.923)
[121] Chen L, Liu H, Ji Y, et al. Downregulation of SHMT2 promotes the prostate cancer proliferation and metastasis by inducing epithelial-mesenchymal transition. Exp Cell Res. 2022;415(2):113138. doi:10.1016/j.yexcr.2022.113138(IF:3.905)
[122] Wu F, Niu Z, Zhou B, Li P, Qian F. PSMB1 Negatively Regulates the Innate Antiviral Immunity by Facilitating Degradation of IKK-ε. Viruses. 2019;11(2):99. Published 2019 Jan 24. doi:10.3390/v11020099(IF:3.811)
[123] Zhou W, Zhang B, Fan K, Yin X, Liu J, Gou S. An Original Aspirin-Containing Carbonic Anhydrase 9 Inhibitor Overcomes Hypoxia-Induced Drug Resistance to Enhance the Efficacy of Myocardial Protection. Cardiovasc Drugs Ther. 2022;36(4):605-618. doi:10.1007/s10557-021-07182-2(IF:3.727)
[124] Yang Y, Xiang K, Sun D, et al. Withanolides from dietary tomatillo suppress HT1080 cancer cell growth by targeting mutant IDH1 [published correction appears in Bioorg Med Chem. 2022 Mar 15;58:116655]. Bioorg Med Chem. 2021;36:116095. doi:10.1016/j.bmc.2021.116095(IF:3.641)
[125] Wang C, Su L, Shao YM, et al. Involvement of PML-I in reformation of PML nuclear bodies in acute promyelocytic leukemia cells by leptomycin B. Toxicol Appl Pharmacol. 2019;384:114775. doi:10.1016/j.taap.2019.114775(IF:3.585)
[126] You Y, Cui Y, Li Y, et al. Inhibition of MTA2 and MTA3 induces mesendoderm specification of human embryonic stem cells. Biochem Biophys Res Commun. 2021;552:142-149. doi:10.1016/j.bbrc.2021.03.030(IF:3.575)
[127] Hu S, Ouyang J, Zheng G, et al. Identification of mutant p53-specific proteins interaction network using TurboID-based proximity labeling. Biochem Biophys Res Commun. 2022;615:163-171. doi:10.1016/j.bbrc.2022.05.046(IF:3.575)
[128] Meng J, Zhang C, Wang D, Zhu L, Wang L. Mitochondrial GCN5L1 regulates cytosolic redox state and hepatic gluconeogenesis via glycerol phosphate shuttle GPD2 [published online ahead of print, 2022 Jun 28]. Biochem Biophys Res Commun. 2022;621:1-7. doi:10.1016/j.bbrc.2022.06.092(IF:3.575)
[129] Wang HD, Guo LJ, Feng ZQ, et al. Cloning, expression and enzyme activity delineation of two novel CANT1 mutations: the disappearance of dimerization may indicate the change of protein conformation and even function. Orphanet J Rare Dis. 2020;15(1):240. Published 2020 Sep 9. doi:10.1186/s13023-020-01492-8(IF:3.523)
[130] Li P, Jin Y, Qi F, et al. SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65. Front Cell Infect Microbiol. 2018;8:113. Published 2018 Apr 9. doi:10.3389/fcimb.2018.00113(IF:3.520)
[131] Wang Z, Wu J, Jiang J, et al. KIF2A decreases IL-33 production and attenuates allergic asthmatic inflammation. Allergy Asthma Clin Immunol. 2022;18(1):55. Published 2022 Jun 19. doi:10.1186/s13223-022-00697-9(IF:3.406)
[132] Wu D, Lu W, Wei Z, Xu M, Liu X. Neuroprotective Effect of Sirt2-specific Inhibitor AK-7 Against Acute Cerebral Ischemia is P38 Activation-dependent in Mice [published correction appears in Neuroscience. 2018 May 9;:]. Neuroscience. 2018;374:61-69. doi:10.1016/j.neuroscience.2018.01.040(IF:3.382)
[133] Yang J, Shen Y, Yang X, et al. Silencing of long noncoding RNA XIST protects against renal interstitial fibrosis in diabetic nephropathy via microRNA-93-5p-mediated inhibition of CDKN1A. Am J Physiol Renal Physiol. 2019;317(5):F1350-F1358. doi:10.1152/ajprenal.00254.2019(IF:3.323)
[134] Yan JM, Zhang WK, Li F, Zhou CM, Yu XJ. Integrated transcriptome profiling in THP-1 macrophages infected with bunyavirus SFTSV. Virus Res. 2021;306:198594. doi:10.1016/j.virusres.2021.198594(IF:3.303)
[135] Luo L, Zhu D, Huang R, et al. Molecular cloning and preliminary functional analysis of six RING-between-ring (RBR) genes in grass carp (Ctenopharyngodon idellus). Fish Shellfish Immunol. 2019;87:62-72. doi:10.1016/j.fsi.2018.12.078(IF:3.298)
[136] Abudurexiti M, Zhu W, Wang Y, et al. Targeting CPT1B as a potential therapeutic strategy in castration-resistant and enzalutamide-resistant prostate cancer. Prostate. 2020;80(12):950-961. doi:10.1002/pros.24027(IF:3.279)
[137] Li F, Su M, Zhao H, et al. HnRNP-F promotes cell proliferation by regulating TPX2 in bladder cancer. Am J Transl Res. 2019;11(11):7035-7048. Published 2019 Nov 15. (IF:3.266)
[138] Sun H, Han L, Zhang X, et al. Case Report: Characterization of a Novel NONO Intronic Mutation in a Fetus With X-Linked Syndromic Mental Retardation-34. Front Genet. 2020;11:593688. Published 2020 Nov 16. doi:10.3389/fgene.2020.593688(IF:3.260)
[139] Li Y, Zhu T, Yang H, et al. Nav1.7 is phosphorylated by Fyn tyrosine kinase which modulates channel expression and gating in a cell type-dependent manner. Mol Pain. 2018;14:1744806918782229. doi:10.1177/1744806918782229(IF:3.205)
[140] Zhu D, Huang R, Chen L, et al. Cloning and characterization of the LEF/TCF gene family in grass carp (Ctenopharyngodon idella) and their expression profiles in response to grass carp reovirus infection. Fish Shellfish Immunol. 2019;86:335-346. doi:10.1016/j.fsi.2018.11.057(IF:3.185)
[141] Li W, Luo L, Shi W, Yin Y, Gao S. Ursolic acid reduces Adriamycin resistance of human ovarian cancer cells through promoting the HuR translocation from cytoplasm to nucleus. Environ Toxicol. 2021;36(2):267-275. doi:10.1002/tox.23032(IF:3.118)
[142] Wang J, Lu Y, Zeng Y, Zhang L, Ke K, Guo Y. Expression profile and biological function of miR-455-5p in colorectal carcinoma. Oncol Lett. 2019;17(2):2131-2140. doi:10.3892/ol.2018.9862(IF:2.967)
[143] Zhou XM, Liu J, Wang Y, et al. microRNA-129-5p involved in the neuroprotective effect of dexmedetomidine on hypoxic-ischemic brain injury by targeting COL3A1 through the Wnt/β-catenin signaling pathway in neonatal rats [published online ahead of print, 2018 Jan 27] [retracted in:  J Cell Biochem. 2021 Nov;122 Suppl 1:S92]. J Cell Biochem. 2018;10.1002/jcb.26704. doi:10.1002/jcb.26704(IF:2.959)
[144] Zhu C, Song Z, Chen Z, et al. MicroRNA-4735-3p Facilitates Ferroptosis in Clear Cell Renal Cell Carcinoma by Targeting SLC40A1. Anal Cell Pathol (Amst). 2022;2022:4213401. Published 2022 May 19. doi:10.1155/2022/4213401(IF:2.916)
[145] Wang X, Ye M, Wu M, et al. RNF213 suppresses carcinogenesis in glioblastoma by affecting MAPK/JNK signaling pathway. Clin Transl Oncol. 2020;22(9):1506-1516. doi:10.1007/s12094-020-02286-x(IF:2.737)
[146] Wang N, Zeng GZ, Yin JL, Bian ZX. Artesunate activates the ATF4-CHOP-CHAC1 pathway and affects ferroptosis in Burkitt's Lymphoma. Biochem Biophys Res Commun. 2019;519(3):533-539. doi:10.1016/j.bbrc.2019.09.023(IF:2.705)
[147] Li Y, Qin G, Du J, Yue P, Zhang Y, Hou N. circRNA LDLRAD3 Enhances the Malignant Behaviors of NSCLC Cells via the miR-20a-5p-SLC7A5 Axis Activating the mTORC1 Signaling Pathway. J Healthc Eng. 2022;2022:2373580. Published 2022 Jan 6. doi:10.1155/2022/2373580(IF:2.682)
[148] Zhe J, Chen S, Chen X, et al. A novel heterozygous splice-altering mutation in HFM1 may be a cause of premature ovarian insufficiency. J Ovarian Res. 2019;12(1):61. Published 2019 Jul 6. doi:10.1186/s13048-019-0537-x(IF:2.469)
[149] Shang J, Chen WM, Wang ZH, Wei TN, Chen ZZ, Wu WB. CircPAN3 mediates drug resistance in acute myeloid leukemia through the miR-153-5p/miR-183-5p-XIAP axis. Exp Hematol. 2019;70:42-54.e3. doi:10.1016/j.exphem.2018.10.011(IF:2.436)
[150] Yu T, Ling Q, Xu M, et al. ORF8 protein of SARS-CoV-2 reduces male fertility in mice. J Med Virol. 2022;94(9):4193-4205. doi:10.1002/jmv.27855(IF:2.327)
[151] Dai Y, Nie J, Luo Z, Nie D. Expression profile analysis of a new testis-specifically expressed gene C17ORF64 and its association with cell apoptosis in MCF-7 cells. Mol Biol Rep. 2021;48(2):1521-1529. doi:10.1007/s11033-021-06191-6(IF:2.316)
[152] Jiang T, Zhou B, Li YM, Yang QY, Tu KJ, Li LY. ALOX12B promotes carcinogenesis in cervical cancer by regulating the PI3K/ERK1 signaling pathway. Oncol Lett. 2020;20(2):1360-1368. doi:10.3892/ol.2020.11641(IF:2.311)
[153] Wei P, Guo J, Xue W, Zhao Y, Yang J, Wang J. RNF34 modulates the mitochondrial biogenesis and exercise capacity in muscle and lipid metabolism through ubiquitination of PGC-1 in Drosophila. Acta Biochim Biophys Sin (Shanghai). 2018;50(10):1038-1046. doi:10.1093/abbs/gmy106(IF:2.224)
[154] He L, Fan X, Li Y, et al. Aberrant methylation status of SPG20 promoter in hepatocellular carcinoma: A potential tumor metastasis biomarker. Cancer Genet. 2019;233-234:48-55. doi:10.1016/j.cancergen.2019.04.003(IF:2.183)
[155] Gao X, Peng S, Mei S, et al. Expression and functional identification of recombinant SARS-CoV-2 receptor binding domain (RBD) from E. coli system. Prep Biochem Biotechnol. 2022;52(3):318-324. doi:10.1080/10826068.2021.1941106(IF:2.162)
[156] Li H, Dai Y, Luo Z, Nie D. Cloning of a new testis-enriched gene C4orf22 and its role in cell cycle and apoptosis in mouse spermatogenic cells. Mol Biol Rep. 2019;46(2):2029-2038. doi:10.1007/s11033-019-04651-8(IF:2.107)
[157] Shang J, Chen WM, Liu S, et al. CircPAN3 contributes to drug resistance in acute myeloid leukemia through regulation of autophagy. Leuk Res. 2019;85:106198. doi:10.1016/j.leukres.2019.106198(IF:2.066)
[158] Qiu C, Li C, Tong X, et al. A novel TSC1 frameshift mutation c.1550_1551del causes tuberous sclerosis complex by aberrant splicing and nonsense-mediated mRNA degradation (NMD) simultaneously in a Chinese family. Mol Genet Genomic Med. 2020;8(10):e1410. doi:10.1002/mgg3.1410(IF:1.995)
[159] Ding K, Jiang J, Chen L, Xu X. Methylenetetrahydrofolate Dehydrogenase 1 Silencing Expedites the Apoptosis of Non-Small Cell Lung Cancer Cells via Modulating DNA Methylation. Med Sci Monit. 2018;24:7499-7507. Published 2018 Oct 21. doi:10.12659/MSM.910265(IF:1.894)
[160] Liu L, Sun L, Zheng J, Wang Y. Silencing BRIT1 Facilitates the Abilities of Invasiveness and Migration in Trophoblast Cells. Med Sci Monit. 2018;24:7451-7458. Published 2018 Oct 19. doi:10.12659/MSM.910229(IF:1.894)
[161] Li B, Zhang J, Su Y, et al. Overexpression of PTEN may increase the effect of pemetrexed on A549 cells via inhibition of the PI3K/AKT/mTOR pathway and carbohydrate metabolism. Mol Med Rep. 2019;20(4):3793-3801. doi:10.3892/mmr.2019.10617(IF:1.851)
[162] Gao X, Liang K, Mei S, Peng S, Vong EG, Zhan J. An efficient system to generate truncated human angiotensin converting enzyme 2 (hACE2) capable of binding RBD and spike protein of SARS-CoV2. Protein Expr Purif. 2021;184:105889. doi:10.1016/j.pep.2021.105889(IF:1.650)
[163] Deng J, Li D, Mei H, Tang L, Wang HF, Hu Y. Novel deep intronic mutation in the coagulation factor XIII a chain gene leading to unexpected RNA splicing in a patient with factor XIII deficiency. BMC Med Genet. 2020;21(1):9. Published 2020 Jan 8. doi:10.1186/s12881-019-0944-2(IF:1.585)
[164] Su DN, Wu SP, Chen HT, He JH. HOTAIR, a long non-coding RNA driver of malignancy whose expression is activated by FOXC1, negatively regulates miRNA-1 in hepatocellular carcinoma. Oncol Lett. 2016;12(5):4061-4067. doi:10.3892/ol.2016.5127(IF:1.482)
[165] Liao PC, Franco-Iborra S, Yang Y, Pon LA. Live cell imaging of mitochondrial redox state in mammalian cells and yeast. Methods Cell Biol. 2020;155:295-319. doi:10.1016/bs.mcb.2019.11.008(IF:1.441)
[166] Chen X, Lin Z, Hu J, et al. Report of Two Novel Thalassemia Variants, HBB: c.181delG and HBA1: c.121_126delAAGACC, in Chinese Individuals. Hemoglobin. 2021;45(1):52-55. doi:10.1080/03630269.2021.1883646(IF:0.849)
[167] Lin T, Yang Y, Ye X, Yao J, Zhou H. Low expression of miR-99b promotes progression of clear cell renal cell carcinoma by up-regulating IGF1R/Akt/mTOR signaling. Int J Clin Exp Pathol. 2020;13(12):3083-3091. Published 2020 Dec 1. (IF:0.252)
[168] Zhang Q, Tao C, Gao S, et al. Homozygous variant in KASH5 causes premature ovarian insufficiency by disordered meiotic homologous pairing [published online ahead of print, 2022 Jun 16]. J Clin Endocrinol Metab. 2022;dgac368. doi:10.1210/clinem/dgac368(IF:0.000)
[169] Liu W, Shi X, Li Y, Qiao F, Wu Y. The identification of a novel splicing mutation in the DMD gene of a Chinese family. Clin Case Rep. 2021;9(12):e05166. Published 2021 Dec 9. doi:10.1002/ccr3.5166(IF:0.000)