创新平台
INNOVATION PLATFORM
翌圣生物目前涵盖自主研发的6大核心技术平台，集成了20项核心技术，平台与技术之间相互协同，互为补充，由此打通了分子酶、蛋白、抗体.核酸、细胞的技术开发路径。其中，双向分子酶理性设计与定向进化平台、蛋白高密度发酵与超洁净纯化平台和高性能单克隆抗体研发平台共同为分子诊断试剂关键原料研发平台、高通量测序建库试剂创新研发平台和mRNA医药应用研发平台提供研发和生产的关键原料，保障了公司核心原料品质的稳定和供应链的安全可控。
Multimodal supramolecular targeting chimeras enable spatiotemporally resolved protein degradation in vivo
LncRNA-encoded microproteins: A new form of cargo in cell culture-derived and circulating extracellular vesicles
Bacteroides fragilis toxin promotes gall bladder cancer in mice
Quantitative Membrane Paramagnetic Relaxation Enhancement (mPRE) Measurements on Lipid-Anchored Proteins: Insight into Orientational Dynamics
Super-enhancer-driven core transcription factor FOXP1 delays endothelial cell senescence via phase separation-mediated SESN3 activation
Patient-Derived 3D-Bioprinted Intrahepatic Cholangiocarcinoma Models Recapitulate Tumor Autologous Traits and Predict Personalized Adjuvant Therapy
Intrinsically Mitochondria-Targeting Nanozyme via Coordination-Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia-Reperfusion Injury
A Conserved DT2-bZIP66-NF-YC4 Regulatory Module Confers Drought Tolerance in Rice and Arabidopsis
Human Urine Stem Cells Alleviate Pulmonary Fibrosis via Inhibiting Macrophage-Myofibroblast Transition
Single-Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti-PD-1 Resistance in Colorectal Cancer
Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction
Targeting the HSPA8-CMA-ATP6V1A Axis Triggers Lysosomal Hyperacidification and Catastrophic Vacuolation in Prostate Cancer
ERF Transcription Factor NaERFIDOG Regulates JA-Induced Defence and Growth Inhibition in Nicotiana attenuata Upon Alternaria alternata Infection
Activated hepatic stellate cell membrane-camouflaged nanomedicine enables targeted HDAC6 inhibition for liver fibrosis therapy
Lactate-activated astrocytes promote NSCLC brain metastasis through extracellular vesicle-mediated miR-8085/TRIM67/ELK1 signaling axis
Targeting IL-1α Sensitizes HNSCC to PDT by Reversing Hypoxia and NF-κB-Driven Oxidative Stress Resistance
USP1-mediated lipophagy-lipogenesis axis drives cholangiocarcinoma progression and immune evasion
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Integrated network toxicology and transcriptomics reveal NF-κB signaling as a key mediator of TDCPP-induced inflammatory responses in human microglia
Macrophage-biomimetic anti-inflammatory liposomes for homing and treating of aortic dissection
